Many chocolate products contain toxic heavy metals: new study

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This is a bitter pill to swallow. Many cocoa products in the US contain concerning levels of toxic heavy metals, a new study from George Washington University warns. Many cocoa products in the US contain worrisome levels of lead and cadmium, a new study from George Washington University warns. Picture Partners – stock.adobe.com Researchers analyzed 72 cocoa-based foods — including dark chocolate, often praised as a heart-healthy treat — over eight years. They found that 43% of the products contained an amount of lead that tops recommendations, while 35% exceeded cadmium limits. Surprisingly, organic-labeled products had higher levels of lead and cadmium than non-organic products, the researchers said. Contamination can come from soil or occur during manufacturing. A single serving of these cocoa items may not pose significant health risks, but several servings might. Leigh Frame, director of integrative medicine at GW, led the testing of 72 cocoa-based products. The George Washingto...

New 3D embryo imaging method may improve IVF outcomes: study



Researchers say they have developed a 3D imaging model of early-stage embryos that may make it easier for women to get pregnant through in vitro fertilization (IVF).

About 2.5% of US births — nearly 92,000 — were from IVF in 2022. When IVF patients create several embryos, it can be difficult to determine which ones have the best chance of resulting in birth.

Now, scientists in China say their 3D model of blastocysts — embryos that are around 5 or 6 days old — can provide previously unknown details about cell features that have been associated with successful pregnancies.

“This study shows that the 3D shape of the blastocyst’s inner cell mass, its position, and how the surrounding cells are arranged can be important indicators of success, which we didn’t know before,” said lead study author Dr. Bo Huang, an embryologist at the Reproductive Medicine Center of Tongji Hospital in China.

Researchers say they have developed a 3D imaging model of early-stage embryos that may make it easier for women to get pregnant through in vitro fertilization. Seventyfour – stock.adobe.com

In IVF, eggs are collected from a woman and combined with sperm in a lab to create embryos, which are placed into the uterus.

About 2.5% of US births — nearly 92,000 — were from IVF in 2022. Getty Images/iStockphoto

Patients can get their embryos tested for genetic abnormalities before transfer. The success rate is 60% to 65% for genetically healthy embryos. These odds diminish when the woman is older or has uterus conditions that make it difficult for an embryo to implant.

This new study included women younger than 40 with a thick uterine lining and no more than one failed embryo transfer. Using EmbryoScope+, technology that can monitor the development of embryos, researchers took detailed images of 2,141 blastocysts.

They compared their model with fluorescence imaging of the blastocysts and found it was 90% accurate.

“Traditionally, the quality of blastocysts is assessed using 2D methods that lack depth and comprehensive indicators,” Huang explained. “Although some 3D methods exist, they aren’t practical or safe for clinical use. This study bridges that gap by introducing a clinically applicable 3D evaluation method and reveals previously unrecognized … features of blastocysts.”

Huang’s research, published in the journal Human Reproduction, was presented Monday in Amsterdam at the annual meeting of the European Society of Human Reproduction and Embryology (ESHRE).

He said the ultimate goal is to make this technology a standard in IVF, bringing new hope to patients.

Scientists in China say their 3D model of blastocysts — embryos that are around 5 or 6 days old — can yield previously unknown details about cell features that have been associated with successful pregnancies. Andriy Bezuglov – stock.adobe.com

Dr. Anis Feki, chair-elect of ESHRE, said Huang’s model “shows great promise,” but further research is needed.

“This method could potentially enhance IVF outcomes, but its clinical application should be approached with careful consideration,” Feki added.



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